Stochastic Modeling of Blood Coagulation Initiation
نویسندگان
چکیده
منابع مشابه
Stochastic modeling of blood coagulation initiation.
A kinetic Monte Carlo simulation was developed using the deterministic reaction network developed by the Mann laboratory for tissue-factor (TF)-initiated blood coagulation. The model predicted thrombin dynamics in recalcified whole blood (3-fold diluted) pretreated with convulxin (platelet GPVI activator) and picomolar levels of TF (0-14 pM). The model did not accurately predict coagulation tim...
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In the last years, the use of Graphical Processing Units (GPUs) has witnessed ever growing applications for different computational analyses in the field of Life Sciences. In this work we present a CUDA-powered computational tool for the simulation of biological models defined as systems of mixed ordinary differential equations, based on both mass-action kinetics and Hill functions. The tool, n...
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ژورنال
عنوان ژورنال: Pathophysiology of Haemostasis and Thrombosis
سال: 2005
ISSN: 1424-8832,1424-8840
DOI: 10.1159/000089929